A new 3D-structure, made from cryo-electron microscopy imaging, of a cancer-linked protein bound to its cellular partner ...

It has been known for several years that abnormal chromosome numbers lead to protein imbalances in the affected cells. Researchers at RPTU have now investigated the detailed effects of such imbalances ...

New findings reveal an advanced, unexpected two-way communication between the function and organization of chromosomes in the cell nucleus. Previous research shows that the organization of chromosomal ...

A hallmark of cancerous cells is an abnormal number of chromosomes or chromosome arms, known as aneuploidy. While aneuploidy is detrimental to regular cells, it occurs in as many as 90% of tumors. How ...

In a study published in the journal Science, researchers in Queensland and the United States discovered that the human X chromosome attracts an unusual kind of DNA mutation, potentially doubling the ...

Researchers have made a surprising new discovery in the structure of the centromere, a structure that is involved in ensuring that chromosomes are segregated properly when a cell divides. Mistakes in ...

Human sex chromosomes originated from a pair of autosomes, the ordinary or non-sex chromosomes that contain the majority of our genome and come in identical pairs. That ancestral pair of autosomes ...

WHEN THE first draft of the DNA sequence that makes up the human genome was unveiled in 2000, America’s president at the time, Bill Clinton, announced that humankind was “learning the language with ...

For decades, gene therapy has focused on correcting faulty genes or replacing missing ones. Now, scientists are exploring an even more ambitious approach, building entirely new chromosomes from ...