Researchers engineered a panel of drug-resistant NSCLC models using CRISPR gene editing and gene overexpression techniques.

Newcells provides a reliable and quick in vitro safety and efficacy service for evaluating novel compounds for retinal therapy with complex human retinal organoid or retinal pigment epithelium (RPE) ...

Cell and gene therapies are exciting new modalities that have the potential to treat, and even cure, a range of diseases that may not be possible with small molecules or monoclonal antibodies. However ...

Chimeric antigen receptor (CAR) T-cell therapy shows significant potential in treating various human cancers. Unfortunately, researchers have faced difficulty in adapting this therapy to target solid ...

Nanoparticle-mediated hyperthermia for cancer therapy is a growing area of cancer nanomedicine because of the potential for localized and targeted destruction of cancer cells. Localized hyperthermal ...

A UCLA-led team has developed a machine-learning model that can predict with a high degree of accuracy the short-term survival of dialysis patients on continuous renal replacement therapy (CRRT). The ...

Spinal muscular atrophy (SMA) is a rare but serious neuromuscular disorder that causes worsening muscle weakness. SMA is a genetic, or inherited, disorder caused by a change in the SMN1 gene that ...

The results of a recent modeling study for gold nanoparticles have shown that the effect of vapor formation, and changes in the thermal conductivity and dielectric properties of the surrounding medium ...